Dr Raida Al Kassas
Pharmacy and Biomolecular Sciences
Faculty of Science
Email: R.AlKassas@ljmu.ac.uk
Telephone: 0151 904 6185
Highlighted publications
Duncan B, Al-Kassas R, Zhang G, Hughes D, Qiu Y. 2023. Ultrasound-Mediated Ocular Drug Delivery: From Physics and Instrumentation to Future Directions Micromachines, 14 DOI Author Url Publisher Url Public Url
Smith M, Roberts M, Al Kassas R. 2022. Implantable drug delivery systems for the treatment of osteomyelitis Espinoza MORAGA. Drug Development and Industrial Pharmacy, DOI Author Url Publisher Url Public Url
Fawcett SA, Al Kassas R, Dykes IM, Hughes AT, Ghali F, Ross K. 2022. A Time to Heal: MicroRNA and Circadian Dynamics in Cutaneous Wound Repair Clinical Science, 136 :579-597 DOI Author Url Publisher Url Public Url
Jay-Smith M, Wang ZL, Al Kassas R, Murphy EC, Shapiro L, Eason CT, Brimble MA, Rennison D. 2021. Separation, characterisation and biological evaluation of the individual isomers of the rat selective toxicant norbormide – isolated using a chemical derivatization strategy Arkivoc, 2021 DOI Author Url Publisher Url Public Url
Al-Kassas R, Madni A, Buchanan C, Shelling A. 2021. pH- sensitive nanoparticles developed and optimized using factorial design for oral delivery of gliclazide Asadullah A, Buchanan C. Journal of Pharmaceutical Innovation, DOI Author Url Publisher Url Public Url
Ta Q, Ting J, Harwood S, Browning N, Simm A, Ross K, Olier I, Al-Kassas R. 2021. Chitosan nanoparticles for enhancing drugs and cosmetic components penetration through the skin European Journal of Pharmaceutical Sciences, DOI Author Url Publisher Url Public Url
Hsi S-L, Surman P, Al-Kassas R. 2019. Development of a stability-indicating UPLC method for determination of isotretinoin in bulk drug Pharmaceutical Development and Technology, 24 :189-198 DOI Author Url Publisher Url Public Url
Al Kassas R, Bansal M, Shaw J. 2017. Nanosizing techniques for improving bioavailability of drugs Journal of Controlled Release, 260 :202-212 DOI Author Url Publisher Url Public Url
Cerqueira BBS, Lasham A, Shelling AN, Al-Kassas R. 2017. Development of biodegradable PLGA nanoparticles surface engineered with hyaluronic acid for targeted delivery of paclitaxel to triple negative breast cancer cells Materials Science and Engineering: C, 76 :593-600 DOI Author Url Publisher Url Public Url
Al-Kassas R, Wen J, Cheng AE-M, Kim AM-J, Liu SSM, Yu J. 2016. Transdermal delivery of propranolol hydrochloride through chitosan nanoparticles dispersed in mucoadhesive gel Carbohydrate Polymers, 153 :176-186 DOI Author Url Publisher Url Public Url
Duxfield L, Sultana R, Wang R, Englebretsen V, Deo S, Swift S, Rupenthal I, Al-Kassas R. 2016. Development of gatifloxacin-loaded cationic polymeric nanoparticles for ocular drug delivery PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 21 :172-179 DOI Author Url Publisher Url
Duxfield L, Sultana R, Wang R, Englebretsen V, Deo S, Rupenthal ID, Al-Kassas R. 2016. Ocular delivery systems for topical application of anti-infective agents DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 42 :1-11 DOI Author Url Publisher Url
Seyfoddin A, Sherwin T, Patel DV, McGhee CN, Rupenthal ID, Taylor JA, Al-Kassas R. 2016. Ex vivo and In vivo Evaluation of Chitosan Coated Nanostructured Lipid Carriers for Ocular Delivery of Acyclovir Current Drug Delivery, 13 :923-934 DOI Author Url Publisher Url Public Url
Alzaher W, Shaw J, Al-Kassas R. 2016. Gastroretentive Formulations for Improving Oral Bioavailability of Drugs-Focus on Microspheres and their Production Current Drug Delivery, 13 :646-661 DOI Author Url Publisher Url Public Url
Cerqueira BBS, Lasham A, Shelling AN, Al-Kassas R. 2015. Nanoparticle therapeutics: Technologies and methods for overcoming cancer EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 97 :140-151 DOI Author Url Publisher Url
Tharkar P, Madani AU, Lasham A, Shelling AN, Al-Kassas R. 2015. Nanoparticulate carriers: an emerging tool for breast cancer therapy JOURNAL OF DRUG TARGETING, 23 :97-108 DOI Author Url Publisher Url
Madni A, Sarfraz M, Rehman M, Ahmad M, Akhtar N, Ahmad S, Tahir N, Ijaz S, Al-Kassas R, Loebenberg R. 2014. Liposomal Drug Delivery: A Versatile Platform for Challenging Clinical Applications JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, 17 :401-426 DOI Author Url Publisher Url
Kuntworbe N, Ofori M, Addo P, Tingle M, Al-Kassas R. 2013. Pharmacokinetics and in vivo chemosuppressive activity studies on cryptolepine hydrochloride and cryptolepine hydrochloride-loaded gelatine nanoformulation designed for parenteral administration for the treatment of malaria ACTA TROPICA, 127 :165-173 DOI Author Url Publisher Url
Kuntworbe N, Alany RG, Brimble M, Al-Kassas R. 2013. Determination of pKa and forced degradation of the indoloquinoline antimalarial compound cryptolepine hydrochloride PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 18 :866-876 DOI Author Url Publisher Url
Seyfoddin A, Al-Kassas R. 2013. Development of solid lipid nanoparticles and nanostructured lipid carriers for improving ocular delivery of acyclovir DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 39 :508-519 DOI Author Url Publisher Url
Awasthi A, Razzak M, Al-Kassas R, Harvey J, Garg S. 2013. Evaluation of degradation kinetics for abamectin in formulations using a stability indicating method ACTA PHARMACEUTICA, 63 :59-69 DOI Author Url Publisher Url
Journal article
Duncan B, Al-Kassas R, Zhang G, Hughes D, Qiu Y. 2023. Ultrasound-Mediated Ocular Drug Delivery: From Physics and Instrumentation to Future Directions Micromachines, 14 DOI Author Url Publisher Url Public Url
Smith M, Roberts M, Al Kassas R. 2022. Implantable drug delivery systems for the treatment of osteomyelitis Espinoza MORAGA. Drug Development and Industrial Pharmacy, DOI Author Url Publisher Url Public Url
Fawcett SA, Al Kassas R, Dykes IM, Hughes AT, Ghali F, Ross K. 2022. A Time to Heal: MicroRNA and Circadian Dynamics in Cutaneous Wound Repair Clinical Science, 136 :579-597 DOI Author Url Publisher Url Public Url
Jay-Smith M, Wang ZL, Al Kassas R, Murphy EC, Shapiro L, Eason CT, Brimble MA, Rennison D. 2021. Separation, characterisation and biological evaluation of the individual isomers of the rat selective toxicant norbormide – isolated using a chemical derivatization strategy Arkivoc, 2021 DOI Author Url Publisher Url Public Url
Al-Kassas R, Madni A, Buchanan C, Shelling A. 2021. pH- sensitive nanoparticles developed and optimized using factorial design for oral delivery of gliclazide Asadullah A, Buchanan C. Journal of Pharmaceutical Innovation, DOI Author Url Publisher Url Public Url
Ta Q, Ting J, Harwood S, Browning N, Simm A, Ross K, Olier I, Al-Kassas R. 2021. Chitosan nanoparticles for enhancing drugs and cosmetic components penetration through the skin European Journal of Pharmaceutical Sciences, DOI Author Url Publisher Url Public Url
Hsi S-L, Surman P, Al-Kassas R. 2019. Development of a stability-indicating UPLC method for determination of isotretinoin in bulk drug Pharmaceutical Development and Technology, 24 :189-198 DOI Author Url Publisher Url Public Url
Al Kassas R, Bansal M, Shaw J. 2017. Nanosizing techniques for improving bioavailability of drugs Journal of Controlled Release, 260 :202-212 DOI Author Url Publisher Url Public Url
Cerqueira BBS, Lasham A, Shelling AN, Al-Kassas R. 2017. Development of biodegradable PLGA nanoparticles surface engineered with hyaluronic acid for targeted delivery of paclitaxel to triple negative breast cancer cells Materials Science and Engineering: C, 76 :593-600 DOI Author Url Publisher Url Public Url
Al-Kassas R, Wen J, Cheng AE-M, Kim AM-J, Liu SSM, Yu J. 2016. Transdermal delivery of propranolol hydrochloride through chitosan nanoparticles dispersed in mucoadhesive gel Carbohydrate Polymers, 153 :176-186 DOI Author Url Publisher Url Public Url
Duxfield L, Sultana R, Wang R, Englebretsen V, Deo S, Swift S, Rupenthal I, Al-Kassas R. 2016. Development of gatifloxacin-loaded cationic polymeric nanoparticles for ocular drug delivery PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 21 :172-179 DOI Author Url Publisher Url
Duxfield L, Sultana R, Wang R, Englebretsen V, Deo S, Rupenthal ID, Al-Kassas R. 2016. Ocular delivery systems for topical application of anti-infective agents DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 42 :1-11 DOI Author Url Publisher Url
Seyfoddin A, Sherwin T, Patel DV, McGhee CN, Rupenthal ID, Taylor JA, Al-Kassas R. 2016. Ex vivo and In vivo Evaluation of Chitosan Coated Nanostructured Lipid Carriers for Ocular Delivery of Acyclovir Current Drug Delivery, 13 :923-934 DOI Author Url Publisher Url Public Url
Alzaher W, Shaw J, Al-Kassas R. 2016. Gastroretentive Formulations for Improving Oral Bioavailability of Drugs-Focus on Microspheres and their Production Current Drug Delivery, 13 :646-661 DOI Author Url Publisher Url Public Url
Cerqueira BBS, Lasham A, Shelling AN, Al-Kassas R. 2015. Nanoparticle therapeutics: Technologies and methods for overcoming cancer EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 97 :140-151 DOI Author Url Publisher Url
Tharkar P, Madani AU, Lasham A, Shelling AN, Al-Kassas R. 2015. Nanoparticulate carriers: an emerging tool for breast cancer therapy JOURNAL OF DRUG TARGETING, 23 :97-108 DOI Author Url Publisher Url
Svirskis D, Seyfoddin A, Chalabi S, Kim JHI, Langford C, Painter S, Al-Kassas R. 2014. Development of mucoadhesive floating hollow beads of acyclovir with gastroretentive properties PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 19 :571-576 DOI Author Url Publisher Url
Madni A, Sarfraz M, Rehman M, Ahmad M, Akhtar N, Ahmad S, Tahir N, Ijaz S, Al-Kassas R, Loebenberg R. 2014. Liposomal Drug Delivery: A Versatile Platform for Challenging Clinical Applications JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, 17 :401-426 DOI Author Url Publisher Url
Kuntworbe N, Ofori M, Addo P, Tingle M, Al-Kassas R. 2013. Pharmacokinetics and in vivo chemosuppressive activity studies on cryptolepine hydrochloride and cryptolepine hydrochloride-loaded gelatine nanoformulation designed for parenteral administration for the treatment of malaria ACTA TROPICA, 127 :165-173 DOI Author Url Publisher Url
Kuntworbe N, Alany RG, Brimble M, Al-Kassas R. 2013. Determination of pKa and forced degradation of the indoloquinoline antimalarial compound cryptolepine hydrochloride PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 18 :866-876 DOI Author Url Publisher Url
Seyfoddin A, Al-Kassas R. 2013. Development of solid lipid nanoparticles and nanostructured lipid carriers for improving ocular delivery of acyclovir DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 39 :508-519 DOI Author Url Publisher Url
Awasthi A, Razzak M, Al-Kassas R, Harvey J, Garg S. 2013. Evaluation of degradation kinetics for abamectin in formulations using a stability indicating method ACTA PHARMACEUTICA, 63 :59-69 DOI Author Url Publisher Url
Awasthi A, Razzak M, Al-Kassas R, Greenwood DR, Harvey J, Garg S. 2012. Isolation and characterization of degradation products of moxidectin using LC, LTQ FT-MS, H/D exchange and NMR ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 404 :2203-2222 DOI Author Url Publisher Url
Awasthi A, Razzak M, Al-Kassas R, Greenwood DR, Harvey J, Garg S. 2012. Separation and Identification of Degradation Products in Abamectin Formulation Using LC, LTQ FT-MS, H/D Exchange and NMR CURRENT PHARMACEUTICAL ANALYSIS, 8 :415-430 DOI Author Url Publisher Url
Abdelkader H, Wu Z, Al-Kassas R, Alany RG. 2012. Niosomes and discomes for ocular delivery of naltrexone hydrochloride: Morphological, rheological, spreading properties and photo-protective effects INTERNATIONAL JOURNAL OF PHARMACEUTICS, 433 :142-148 DOI Author Url Publisher Url
Awasthi A, Razzak M, Al-Kassas R, Harvey J, Garg S. 2012. An Overview on Chemical Derivatization and Stability Aspects of Selected Avermectin Derivatives CHEMICAL & PHARMACEUTICAL BULLETIN, 60 :931-944 DOI Author Url Publisher Url
Abdelkader H, Ismail S, Hussein A, Wu Z, Al-Kassas R, Alany RG. 2012. Conjunctival and corneal tolerability assessment of ocular naltrexone niosomes and their ingredients on the hen's egg chorioallantoic membrane and excised bovine cornea models INTERNATIONAL JOURNAL OF PHARMACEUTICS, 432 :1-10 DOI Author Url Publisher Url
Fathabadi EG, Shelling AN, Al-Kassas R. 2012. Nanocarrier systems for delivery of siRNA to ovarian cancer tissues EXPERT OPINION ON DRUG DELIVERY, 9 :743-754 DOI Author Url Publisher Url
Kuntworbe N, Martini N, Shaw J, Al-Kassas R. 2012. Malaria Intervention Policies and Pharmaceutical Nanotechnology as a Potential Tool for Malaria Management DRUG DEVELOPMENT RESEARCH, 73 :167-184 DOI Author Url Publisher Url
Kuntworbe N, Al-Kassas R. 2012. Design and In Vitro Haemolytic Evaluation of Cryptolepine Hydrochloride-Loaded Gelatine Nanoparticles as a Novel Approach for the Treatment of Malaria AAPS PHARMSCITECH, 13 :568-581 DOI Author Url Publisher Url
Awasthi A, Razzak M, Al-Kassas R, Greenwood DR, Harvey J, Garg S. 2012. Separation and identification of degradation products in eprinomectin formulation using LC, LTQ FT-MS, H/D exchange, and NMR JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 63 :62-73 DOI Author Url Publisher Url
Al Kassas R, Kuntworbe N, Alany R, Brimble M, Martini N. 2011. Isolation and development of an HPLC method for the detection and quantification of cryptolepine and its application in the determination of the total cryptolepine content in the root powder of Cryptolepis sanguinolenta. Perry G. Pharmacology & Pharmacy, 3
Abdelkader H, Wu Z, Al-Kassas R, Brown JE, Alany RG. 2011. Preformulation characteristics of the opioid growth factor antagonist-naltrexone hydrochloride: stability and lipophilicity studies JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 21 :157-163 DOI Author Url Publisher Url
Gupta J, Tao JQ, Garg S, Al-Kassas R. 2011. Design and Development of an <i>in Vitro</i> Assay for Evaluation of Solid Vaginal Dosage Forms Pharmacology & Pharmacy, 02 :289-298 DOI Publisher Url
Seyfoddin A, Shaw J, Al-Kassas R. 2010. Solid lipid nanoparticles for ocular drug delivery DRUG DELIVERY, 17 :467-489 DOI Author Url Publisher Url
Al-Kassas RS, El-Khatib MM. 2009. Ophthalmic controlled release in situ gelling systems for ciprofloxacin based on polymeric carriers DRUG DELIVERY, 16 :145-152 DOI Author Url Publisher Url
Al-Kassas RS, Al-Gohary OMN, Al-Faadhel MM. 2007. Controlling of systemic absorption of gliclazide through incorporation into alginate beads INTERNATIONAL JOURNAL OF PHARMACEUTICS, 341 :230-237 DOI Author Url Publisher Url
Al-Kassas R. 2004. Design and in vitro evaluation of gentamicin-Eudragit microspheres intended for intra-ocular administration JOURNAL OF MICROENCAPSULATION, 21 :71-81 DOI Author Url Publisher Url
Al-Kassas R. 2003. Interaction study between mebeverine hydrochloride, isoniazid and certain polymers used to prepare multiparticulate delivery systems using differential scanning calorimetry STP PHARMA SCIENCES, 13 :359-366 Author Url
Al-Kassas RS, Rezk NJ. 2003. Enterotoxigenic E-coli colonization factor antigen (CFA/II)-loaded polyisobutylcyanoacrylate nanoparticles for oral immunization STP PHARMA SCIENCES, 13 :93-98 Author Url
Safwat SM, Al-Kassas RS. 2002. Evaluation of gentamicin-Eudragit microspheres as ophthalmic delivery systems in inflamed rabbit's eyes STP PHARMA SCIENCES, 12 :357-361 Author Url
Al Kassas R. 2000. Controlled-release theophylline suppositories containing bioadhesive microspheres Bulletin of Faculty of Pharmacy, Cairo University,
Al-Gohary OMN, Al-Kassas RS. 2000. Stability studies of aspirin-magaldrate double layer tablets Pharmaceutica Acta Helvetiae, 74 :351-360 DOI Author Url Publisher Url
Chapters
Awasthi A, Razzak M, Al-Kassas R, Harvey J, Garg S. 2013. Analytical Profile of Moxidectin Profiles of Drug Substances, Excipients and Related Methodology 38 :315-366 DOI Author Url Publisher Url
Seyfoddin A, Al-Kassas R. 2011. Biodegradable polymers for controlled delivery of bioactive macromolecules Biodegradable Polymers: Processing, Degradation and Applications :471-500
Membership of professional bodies:
Guest Editor for a topic "Pharmaceutical Nanotechnology for Biomedical Applications: Current Advances and Future Prospects", Molecules Journal, https://www.mdpi.com/journal/molecules/special_issues/pharmaceutical_nanotechnology_prospects. 2021
Member, The British Society for Nanomedicine. 2019
Conference presentation:
Design of gliclazide tableted microspheres using hydrophilic polymer: effect of excipients on tablets properties, 5th CVOT Summit 2019, Munich/Germany, Poster presentation. 2019
Hyaluronic Acid Coated PLGA Nanoparticles for Target Delivery of Paclitaxel to Triple Negative Breast Cancer, Australian Pharmacy science association (APSA) conference, Australia, Poster presentation. 2015
“Enhanced solubility and dissolution rate of gatifloxacin by solid dispersion technique., Controlled Release Society conference (CRS), Edinburgh, Scotland, Poster presentation. 2015
Development of Gatifloxacin loaded Eudragit nanoparticles for ocular drug delivery, 41st Annual Meeting and Exposition of the Controlled Release Society, Chicago, USA, Poster presentation. 2014
Effect of cross-linking agent on the characteristics of chitosan nanoparticles designed for the delivery of siRNA to ovarian cancer tissues, XXI International Conference on Bioencapsulation, Berlin, Germany, Berlin, Germany, Poster presentation. 2013
. Evaluation of a Novel Lipid Based Nanoparticulate System for Ocular Drug Delivery., 40th annual meeting & exposition of the Controlled Release Society, Hawaii Convention Center in Honolulu, Hawaii, Honolulu, Hawaii, Oral presentation. 2013